REF 4030241

Candida Detection & Monitoring Kit

Candida species identification — 6 clinically critical species (auris, albicans, krusei, glabrata, parapsilosis, tropicalis) in a single panel. Species-level diagnosis in candidaemia and invasive candidiasis suspicion.

IVD-D CE Qualitative · Species ID UMS Compatible · Multiplex · 2-mix · 4-channel · 96-well · 24/48/96 reactions

Clinical Use

Qualitative species-level identification of 6 clinically critical Candida species — C. auris, C. albicans, C. krusei, C. glabrata, C. parapsilosis, C. tropicalis — in nucleic acid extracts from blood, swab, body fluid, BAL and sputum samples. Used as a supportive diagnostic test in clinical suspicion of candidaemia, invasive candidiasis and fungaemia, particularly in intensive care, haematological malignancy and neutropenic patient populations. Species-level resolution guides antifungal selection and resistance expectations. Results must be interpreted in conjunction with clinical findings, blood culture, patient history and other laboratory results.

This test is designed for qualitative species identification. Cq values must not be interpreted as quantitative or semi-quantitative fungal load results.

Test Design

Targets6 Candida species (auris, albicans, krusei, glabrata, parapsilosis, tropicalis)
Internal controlβ-Globin (co-amplification on HEX channel in each mix)
Format2-mix mastermix · 4-channel readout (FAM, HEX, Cy5, Cy5.5)
Reaction volume10 µL total (1 µL oligo mix + 5 µL master mix + 4 µL template)
Cycle time~50 min
Test typeQualitative multiplex species identification real-time PCR

Mix → Channel → Target Mapping

MixFAMHEXCy5Cy5.5
Mix 1C. aurisInternal ControlC. albicansC. krusei
Mix 2C. glabrataInternal ControlC. parapsilosisC. tropicalis

ROX channel is not used in this kit. HEX carries the internal control (β-Globin) in both mixes.

Kit Contents (24-reaction pack)

Oligo Mix 11 × 24 µL · auris/albicans/krusei + IC primers + probes
Oligo Mix 21 × 24 µL · glabrata/parapsilosis/tropicalis + IC primers + probes
Uniqplex Enzyme Mix1 × 240 µL (2 mix × 120 µL)
NTC1 × 1000 µL · negative control
PC (Positive Control)1 × 120 µL · synthetic 6-species mix

48- and 96-reaction packs are also available — see IFU §3.

Validated Instruments

  • HiMedia InstaQ96
  • Bio-Rad CFX96 Touch
  • Applied Biosystems QuantStudio 5
  • Qiagen Rotor-Gene Q 5plex

Performance

Typical LoD values for DNA targets are in the range of 50–500 copies/mL in extracted samples; target-specific LoD values are documented in the performance evaluation report. The linear amplification range extends approximately 5–6 log₁₀ above the LoD. Analytical specificity and cross-reactivity data are documented in the performance evaluation report.

Storage

Before use (sealed)−20 °C · until expiry date
After opening−20 °C · 4 months (including freeze-thaw)
Freeze-thaw cycleMaximum 3

Regulatory

Class C IVD device. CE marked under the transitional provisions of Regulation (EU) 2017/746. The conformity assessment process under (EU) 2017/746 (IVDR) is ongoing. TİTCK registered. For in vitro diagnostic use only — for laboratory and professional use.